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artemether/lumefantrine will lower the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.cenobamate will improve the level or effect of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Closely. Contemplate a dose reduction of CYP2C19 substrates, as clinically su